Restoration of Interhemispheric Resting-state fMRI Connectivity after Patrial Corpus Callosotomy via Intrahemispheric Reorganization

posterior partial callosotomy and sham surgery at post-surgery day 7 and day 28. The seeds were centered at left/right primary somatosensory cortex (S1)/primary visual cortex (V1), respectively. The transected part of the corpus callosum is indicated in red in the sagittal planes (top left panel) and the anatomical regions of S1 and V1 are highlighted in 3D atlas space (bottom left panel). At day 28, both callosotomy groups exhibited apparent expansions in intraregional rsfMRI connectivity as compared to sham, as indicated by the increased sizes of the clusters covering the seeds.